NCOR1 Polyclonal Antibody

Background:
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction

Synonyms:
hN CoR, hNCoR, KIAA1047, N CoR, N Cor/SMRT corepressor Rip13, N CoR1, N-CoR, N-CoR1, NCOR 1, NCoR, Ncor1, NCOR1, Nuclear receptor co repressor 1, Nuclear receptor corepressor 1, Retinoid X receptor interacting protein 13, RIP13, Rxrip13, thyroid hormone and retinoic acid receptor associated corepressor 1, TRAC 1, TRAC1

Immunogen: Synthetic peptide of human NCOR1

Swissprot: O75376
Gene Accession: NP_006302

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-1609/sc-8994