NCOR1 polyclonal (N-term), anti-human, mouse
€0.00
In stock
SKU
AC-AP1121A
Catalog Number: AC-AP1121A
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2594
Applications: IF, WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB2594
Applications: IF, WB, IHC-P
Datasheet
Request Information
Background:
NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. The gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.
Other Names:
Nuclear receptor corepressor 1, N-CoR, N-CoR1, NCOR1, KIAA1047
Target/Specificity:
This NCOR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-47 amino acids from the N-terminal region of human NCOR1.
Antigen Region:
16-47
Antigen Type: Synthetic Peptide
Gene Name: NCOR1
Gene ID: 9611
Primary Accession: O75376
NCBI Accession: NP_001177367.1;NP_001177369.1;NP_006302.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. The gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.
Other Names:
Nuclear receptor corepressor 1, N-CoR, N-CoR1, NCOR1, KIAA1047
Target/Specificity:
This NCOR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-47 amino acids from the N-terminal region of human NCOR1.
Antigen Region:
16-47
Antigen Type: Synthetic Peptide
Gene Name: NCOR1
Gene ID: 9611
Primary Accession: O75376
NCBI Accession: NP_001177367.1;NP_001177369.1;NP_006302.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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