NDC80 Polyclonal Antibody

Background:
This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms:
NDC80, HEC, HEC1, HsHec1, KNTC2, TID3, hsNDC80

Immunogen: Recombinant fusion protein of human NDC80 (NP_006092.1).

Swissprot: O14777
Gene ID: 10403

Calculated MW: 73 kDa
Observed MW: 80 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.