NDE1 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS8718
Background:
This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe mental retardation. Alternative splicing results in multiple transcript variants.
Alternative Name:
Nuclear distribution protein nudE homolog 1, NudE, NDE1, NUDE
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: NDE1 polyclonal antibody detects endogenous levels of NDE1 protein.
Immunogen:
Recombinant full length Human NDE1.
MW: ~ 39kDa
Swis Prot.: Q9NXR1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe mental retardation. Alternative splicing results in multiple transcript variants.
Alternative Name:
Nuclear distribution protein nudE homolog 1, NudE, NDE1, NUDE
Application Dilution: WB: 1:500~1:2000, IF: 1:50~1:200
Specificity: NDE1 polyclonal antibody detects endogenous levels of NDE1 protein.
Immunogen:
Recombinant full length Human NDE1.
MW: ~ 39kDa
Swis Prot.: Q9NXR1
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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