NDE1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe mental retardation. Alternative splicing results in multiple transcript variants.

Synonyms: HOM-TES-87, LIS4, MHAC, NDE, NUDE, NUDE1

Cellular Location: Cytoskeleton

Immunogen:
Recombinant protein of human NDE1

Gene Symbol: NDE1

Gene ID: 54820

Swiss prot: Q9NXR1

Calculated MW: 39kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.