NDE1 Polyclonal Antibody

Background:
nudE neurodevelopment protein 1(NDE1) Homo sapiens This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012],

Immunogen: Synthesized peptide derived from human protein . at AA range: 270-350

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 38

GeneID: NDE1 NUDE

Storage: -20°C/1 year

NOTE: For Research Use Only