NDN Blocking Peptide (N-term)
€363.00
In stock
SKU
AC-BP20885b
Background:
Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle- promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Functions also as transcription factor and binds directly to specific guanosine-rich DNA sequences (By similarity).
Other Names:
Necdin, NDN
Target/Specificity:
The synthetic peptide sequence is selected from aa 75-89 of HUMAN NDN
Gene Name: NDN
Gene ID: 4692
Primary Accession: Q99608
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle- promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Functions also as transcription factor and binds directly to specific guanosine-rich DNA sequences (By similarity).
Other Names:
Necdin, NDN
Target/Specificity:
The synthetic peptide sequence is selected from aa 75-89 of HUMAN NDN
Gene Name: NDN
Gene ID: 4692
Primary Accession: Q99608
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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