NDN polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP20885b
Catalog Number: AC-AP20885b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB51025
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB51025
Applications: WB
Datasheet
Request Information
Background:
Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle- promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Functions also as transcription factor and binds directly to specific guanosine-rich DNA sequences (By similarity).
Other Names:
Necdin, NDN
Target/Specificity:
This NDN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 75-109 amino acids from the N-terminal region of human NDN.
Gene Name: NDN
Gene ID: 4692
Primary Accession: Q99608
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Growth suppressor that facilitates the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle- promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Functions also as transcription factor and binds directly to specific guanosine-rich DNA sequences (By similarity).
Other Names:
Necdin, NDN
Target/Specificity:
This NDN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 75-109 amino acids from the N-terminal region of human NDN.
Gene Name: NDN
Gene ID: 4692
Primary Accession: Q99608
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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