NDRG1 polyclonal, anti-human, mouse, rat

Background:
The N-myc downstream regulated gene (NDRG) family is comprised of four members, NDRG1 (also designated Drg1, RTP, rit42, Cap43 and Ndr1), NDRG2, NDRG3 and NDRG4, which share 57-65% homology. The NDRG1 gene, which maps to human chromosome 8q24.22, is evolutionarily conserved and is similarly regulated in humans, mice and rats . Like NDRG2 and NDRG3, NDRG1 is ubiquitously expressed, but it is expressed most prominently in placental membranes and prostate, kidney, small intestine and ovary tissue. NDRG1 gene expression is induced by several compounds, including nickel, and produces a protein involved in stress responses, hormone responses, cell growth and differentiation. The gene encoding NDRG3 maps to human chromosome 20q11.23 and is predominantly expressed in testis, prostate and ovary, which suggests it may play a role in spermatogenesis.

Alternative Name:
DRG-1, RTP, NDRG1, CAP43, DRG1, RTP, 42 kDa, Anti GC4, cap43, cmt4d, Differentiation related gene1 protein, Differentiation-related gene 1 protein, Drg 1, DRG-1, drg1, gc4, GC4, antibody, hmsnl, Human mRNA for RTP complete cds, N myc downstream regulated gene 1, N myc downstream regulated gene 1 protein, N-myc downstream-regulated gene 1 protein, Ndr 1, ndr1, NDRG 1, Ndrg1, NDRG1 protein, NDRG1, Nickel specific induction protein, Nickel specific induction protein Cap43, Nickel-specific induction protein Cap43, nmsl, Nmyc downstream regulated, Nmyc downstream regulated gene1, Nmyc downstream regulated gene1 protein, Protein NDRG1, Protein regulated by oxygen 1, Protein regulated by oxygen1, Proxy1, Reduced in tumor, Reducin, Reducing agents and tunicamycin responsive protein, Reducing agents and tunicamycin-responsive protein, Rit42, RTP, targ1, TDD5, tdds, Tunicamycin responsive protein,

Application Dilution:
WB:1:500-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
IP:1:50

Specificity: NDRG1 polyclonal antibody detects endogenous levels of NDRG1 protein.

Immunogen:
Recombinant protein

MW: 43 kDa

Swiss-Prot: Q92597(Human) Q62433(Mouse) Q6JE36(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.