NDUFA1 antibody (clone 3B9-1A1), anti-human
€435.00
In stock
SKU
AC-AT2998a
Catalog Number: AC-AT2998a
Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB
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Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB
Request Information AC-AT2998a">Request Information
Background:
The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the hydrophobic protein (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function.
Other Names:
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1, Complex I-MWFE, CI-MWFE, NADH-ubiquinone oxidoreductase MWFE subunit, NDUFA1
Antigen Type:
Recombinant Protein
Gene Name: NDUFA1
Gene ID: 4694
NCBI Accession: NP_004532.1
Primary Accession: O15239
Other Accession: BC000266
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the hydrophobic protein (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function.
Other Names:
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1, Complex I-MWFE, CI-MWFE, NADH-ubiquinone oxidoreductase MWFE subunit, NDUFA1
Antigen Type:
Recombinant Protein
Gene Name: NDUFA1
Gene ID: 4694
NCBI Accession: NP_004532.1
Primary Accession: O15239
Other Accession: BC000266
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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