NDUFA1 Polyclonal Antibody

Background:
The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
CI MWFE, CI-MWFE, Complex I MWFE, complex I MWFE subunit, Complex I-MWFE, MWFE, MWFE, B. taurus, homolog of, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1 7.5kDa, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1, NADH oxidoreductase subunit MWFE, NADH ubiquinone oxidoreductase (complex 1), NADH ubiquinone oxidoreductase MWFE subunit, NADH-ubiquinone oxidoreductase 1 alpha subcomplex, 1, NADH-ubiquinone oxidoreductase MWFE subunit, NDUA1, NDUFA 1, NDUFA1, Type I dehydrogenase, ZNF 183, ZNF183

Immunogen: Recombinant protein of human NDUFA1

Swissprot: O15239
Gene Accession: BC000266

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-131625