NDUFB11 Polyclonal Antibody

Background:
Complex 1 (also known as NADH dehydrogenase) of the electron transport chain (respiratory chain) is an enzymatic complex that catalyzes the transfer of electrons from NADH to ubiquinone. Free energy from the reaction is conserved in the transfer of protons into the intermembrane space to create an electrochemical proton gradient, a driving force for ATP synthesis. Complex 1 is a complicated, multi-protein, L-shaped complex composed of at least 45 different subunits and located in the mitochondrial inner membrane. NDUFB11 (NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11), also known as ESSS, Np15, Np17.3 (neuronal protein 17.3) or p17.3, is a hydrophobic transmembrane protein belonging to the Complex I NDUFB11 subunit family. Ubiquitously expressed, NDUFB11 localizes to the inner membrane of the mitochondrion and functions as an accessory subunit of Complex I. The cAMP-dependent phosphorylation of NDUFB11 is important for the regulation of Complex I activity.

Research Area: Cancer, Metabolism, Signal transduction, Tags & Cell Markers

Synonyms:
CI ESSS, Complex I ESSS, complex I NP17.3 subunit, ESSS, FLJ20494, MGC111182, NADH dehydrogenase (ubiquinone) 1 beta subcomplex 11 17.3kDa, NADH dehydrogenase (ubiquinone) 1 beta subcomplex 11, NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11 mitochondrial, NADH ubiquinone oxidoreductase ESSS subunit, NDUFB 11, Neuronal protein 17.3, Np15, NP17.3, P17.3

Immunogen: Full length fusion protein

Swissprot: Q9NX14
Gene Accession: BC010665

Calculated MW: 17 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.6 mg/mL
Dilution: WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.