NDUFS2 polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms: CI-49

Cellular Location: Membrane Mitochondrion Mitochondrion inner membrane

Immunogen:
Recombinant protein of human NDUFS2

Gene Symbol: NDUFS2

Gene ID: 4720

Swiss prot: O75306

Calculated MW: 53kDa

Recommended dilution:
WB 1:1000-3000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.