NDUFS2 Polyclonal Antibody

Background:
The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Cell biology, Metabolism, Signal transduction, Tags and Cell markers

Synonyms:
CI 49, CI 49kD, CI-49kD, Complex 1, mitochondrial respiratory chain, 49 KD subunit, Complex I 49kD, Complex I 49kDa subunit, Complex I-49kD, mitochondrial, NADH dehydrogenase (ubiquinone) Fe S protein 2 49kDa, NADH dehydrogenase (ubiquinone) Fe S protein 2, 49kDa (NADH coenzyme Q reductase), NADH dehydrogenase [ubiquinone] iron sulfur protein 2, mitochondrial, NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, NADH ubiquinone oxidoreductase 49 kDa subunit, NADH ubiquinone oxidoreductase NDUFS2 subunit, NADH-ubiquinone oxidoreductase 49 kDa subunit, NADH:ubiquinone oxidoreductase core subunit S2, Ndufs2, NDUS2

Immunogen: Synthetic peptide of human NDUFS2

Swissprot: O75306
Gene Accession: NP_004541

Calculated MW: 53 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.7 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-109593/sc-109595/sc-109594/sc-292086