NDUFS8 Polyclonal Antibody

Background:
This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome.

Research Area: Cancer, Metabolism, Signal Transduction, Tags and Cell Markers

Synonyms:
CI 23kD, CI-23kD, Complex I 23kD, Complex I-23kD, EC 1.6.5.3, EC 1.6.99.3, Human mitochondrial NADH dehydrogenase ubiquinone Fe S protein 8, NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial, NADH ubiquinone oxidoreductase 23 kDa subunit, NADH-ubiquinone oxidoreductase 23 kDa subunit, NDUFS8, NDUS8, TYKY, TYKY subunit, Ubiquinoneiron sulfur protein 8, mitochondrial precursor

Immunogen: Recombinant protein of human NDUFS8

Swissprot: O00217
Gene Accession: BC119754

Calculated MW: 24 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.4 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-243593/sc-243594