NDUFS8 Polyclonal Antibody

Background:
This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome.

Research Area: Cancer, Metabolism, Signal Transduction, Tags and Cell Markers

Synonyms:
NDUFS8, CI-23k, CI23KD, TYKY

Immunogen: Recombinant fusion protein of human NDUFS8 (NP_002487.1).

Swissprot: O00217
Gene ID: 4728

Calculated MW: 23 kDa
Observed MW: 23 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.