NECAB3 Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP10396c
Background:
The protein encoded by this gene interacts with theamino-terminal domain of the neuron-specific X11-like protein(X11L), inhibits the association of X11L with amyloid precursorprotein through a non-competitive mechanism, and abolishes thesuppression of beta-amyloid production by X11L. This protein,together with X11L, may play an important role in the regulatorysystem of amyloid precursor protein metabolism and beta-amyloidgeneration. The protein is phosphorylated by NIMA-related expressedkinase 2, and localizes to the Golgi apparatus. Multiple transcriptvariants encoding different isoforms have been found for this gene.
Other Names:
N-terminal EF-hand calcium-binding protein 3, Amyloid beta A4 protein-binding family A member 2-binding protein, Nek2-interacting protein 1, Neuronal calcium-binding protein 3, X11L-binding protein 51, NECAB3, APBA2BP, NIP1, SYTIP2, XB51
Gene Name: NECAB3
Gene ID: 63941
Primary Accession: Q96P71
Other Accession: NP_112509.3;NP_112508.3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene interacts with theamino-terminal domain of the neuron-specific X11-like protein(X11L), inhibits the association of X11L with amyloid precursorprotein through a non-competitive mechanism, and abolishes thesuppression of beta-amyloid production by X11L. This protein,together with X11L, may play an important role in the regulatorysystem of amyloid precursor protein metabolism and beta-amyloidgeneration. The protein is phosphorylated by NIMA-related expressedkinase 2, and localizes to the Golgi apparatus. Multiple transcriptvariants encoding different isoforms have been found for this gene.
Other Names:
N-terminal EF-hand calcium-binding protein 3, Amyloid beta A4 protein-binding family A member 2-binding protein, Nek2-interacting protein 1, Neuronal calcium-binding protein 3, X11L-binding protein 51, NECAB3, APBA2BP, NIP1, SYTIP2, XB51
Gene Name: NECAB3
Gene ID: 63941
Primary Accession: Q96P71
Other Accession: NP_112509.3;NP_112508.3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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