NECAB3 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS72614
Background:
The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
Alternative Name:
APBA2BP,dJ63M2.4,dJ63M2.5,EFCBP3,NIP1,STIP3,SYTIP2,XB51
Application Dilution: WB: 1:200 - 1:2000
Specificity: NECAB3 polyclonal antibody detects endogenous levels of NECAB3 protein.
Immunogen:
Recombinant protein of human NECAB3
MW: ~ 50 kDa
Swis Prot.: Q96P71
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
Alternative Name:
APBA2BP,dJ63M2.4,dJ63M2.5,EFCBP3,NIP1,STIP3,SYTIP2,XB51
Application Dilution: WB: 1:200 - 1:2000
Specificity: NECAB3 polyclonal antibody detects endogenous levels of NECAB3 protein.
Immunogen:
Recombinant protein of human NECAB3
MW: ~ 50 kDa
Swis Prot.: Q96P71
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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