Nectin 2/CD112 Polyclonal Antibody

Background:
This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Research Area: Cancer, Immunology, Microbiology

Synonyms:
NECTIN2, CD112, HVEB, PRR2, PVRL2, PVRR2, nectin-2

Immunogen: Recombinant fusion protein of human Nectin 2/CD112 (NP_002847.1).

Swissprot: Q92692
Gene ID: 5819

Calculated MW: 51 kDa/57 kDa
Observed MW: 72 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.