NEDD4 polyclonal, anti-human

Background:
This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.

Synonyms: NEDD4-1, RPF1

Cellular Location: Cell membrane Cytoplasm Membrane

Immunogen:
Recombinant protein of human NEDD4

Gene Symbol: NEDD4

Gene ID: 4734

Swiss prot: P46934

Calculated MW: 149kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.