NEDD9 (clone 3F7A9), anti-

Background:
The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Research Area: Cancer, Cell biology, Epigenetics and nuclear signaling

Synonyms: CAS2, CASL, HEF1, CAS-L, CASS2

Immunogen: Purified recombinant fragment of human NEDD9 (AA: 82-398) expressed in E. Coli.

Formulation: Purified antibody in PBS with 0.05% sodium azide

Storage:
4°C|-20°C for long term storage