NEDD9 polyclonal (Center), anti-human

NEDD9 polyclonal (Center), anti-human

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In stock
SKU
AC-AP14592c
Catalog Number: AC-AP14592c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34579
Applications: IHC-P, WB
Datasheet

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Background:
Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May function in transmitting growth control signals between focal adhesions at the cell periphery and the mitotic spindle in response to adhesion or growth factor signals initiating cell proliferation. May play an important role in integrin beta-1 or B cell antigen receptor (BCR) mediated signaling in B-and T-cells. Integrin beta-1 stimulation leads to recruitment of various proteins including CRK, NCK and SHPTP2 to the tyrosine phosphorylated form.

Other Names:
Enhancer of filamentation 1, hEF1, CRK-associated substrate-related protein, CAS-L, CasL, Cas scaffolding protein family member 2, Neural precursor cell expressed developmentally down-regulated protein 9, NEDD-9, Renal carcinoma antigen NY-REN-12, p105, Enhancer of filamentation 1 p55, NEDD9, CASL, CASS2

Target/Specificity:
This NEDD9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 335-363 amino acids from the Central region of human NEDD9.

Antigen Region:
335-363

Antigen Type: Synthetic Peptide

Gene Name: NEDD9 (HGNC:7733)
Gene ID: 4739
Primary Accession: Q14511
NCBI Accession: NP_001135865.1;NP_001257962.1;NP_006394.1;NP_892011.2
Other Accession: NP_006394.1;NP_892011.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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