NEFH antibody (clone 200000000), anti-human

Background:
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.

Other Names:
Neurofilament heavy polypeptide, NF-H, 200 kDa neurofilament protein, Neurofilament triplet H protein, NEFH, KIAA0845, NFH

Antigen Type:
Recombinant Protein

Gene Name: NEFH
Gene ID: 4744
NCBI Accession: NP_066554.2
Primary Accession: P12036
Other Accession: NM_021076
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .