NEFL Antibody (Center R185) Blocking Peptide
€363.00
In stock
SKU
AC-BP7332c
Background:
NEFL is type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. This protein comprises the axoskeleton and it functionally maintains the neuronal caliber. The protein may also play a role in intracellular transport to axons and dendrites. Mutations in this protein cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies.
Other Names:
Neurofilament light polypeptide, NF-L, 68 kDa neurofilament protein, Neurofilament triplet L protein, NEFL, NF68, NFL
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7332c was selected from the Center region of human NEFL. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: NEFL
Gene ID: 4747
Primary Accession: P07196
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
NEFL is type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. This protein comprises the axoskeleton and it functionally maintains the neuronal caliber. The protein may also play a role in intracellular transport to axons and dendrites. Mutations in this protein cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies.
Other Names:
Neurofilament light polypeptide, NF-L, 68 kDa neurofilament protein, Neurofilament triplet L protein, NEFL, NF68, NFL
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7332c was selected from the Center region of human NEFL. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: NEFL
Gene ID: 4747
Primary Accession: P07196
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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