NEFL (clone 1H3), anti-human

NEFL (clone 1H3), anti-human

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In stock
SKU
BT-MCA3400
Catalog Number: BT-MCA3400
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s): WB, IHC, ICC, FCM
Datasheet
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Background:
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.

Research Area: Neuroscience

Synonyms: NFL, NF-L, NF68, CMT1F, CMT2E

Immunogen: Purified recombinant fragment of human NEFL expressed in E. Coli.

Formulation: Ascitic fluid containing 0.03% sodium azide

Storage:
4°C|-20°C for long term storage
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