NEFM polyclonal, anti-human, mouse, rat

Background:
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. 

Synonyms: NFM, NEF3, NF-M

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human NEFM

Gene Symbol: NEFM

Gene ID: 4741

Swiss prot: P07197

Calculated MW: 102 kDa

Recommended dilution:
WB 1:200-1000, IHC 1:25-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.