NEFM Polyclonal Antibody

Background:
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Research Area: Cancer, Developmental Biology, Neuroscience, Signal Transduction, Stem Cells

Synonyms:
NEF3, NF-M, NFM, NEFM

Immunogen: A synthetic peptide of human NEFM (NP_005373.2).

Swissprot: P07197
Gene ID: 4741

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.