NEIL2 polyclonal antibody, anti-human, mouse

Background:
NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002

Research Area: Epigenetics and nuclear signaling

Synonyms: Endonuclease 8-like 2 , EC 3.2.2.-, EC 4.2.99.18, DNA glycosylase/AP lyase Neil2, DNA-, apurinic or apyrimidinic site lyase Neil2, Endonuclease VIII-like 2, Nei homolog 2, NEH2, Nei-like protein

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year