NEK3 polyclonal antibody, anti-mouse

NEK3 polyclonal antibody, anti-mouse

€0.00
In stock
SKU
BT-AP11800
Catalog Number: BT-AP11800
Size(s): 20μL, 50μL, 100μL
Isotype: Rabbit IgG
Reactivity: mouse
Application(s): WB, ELISA
Datasheet
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Background:
This gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Signal transduction

Synonyms: Serine/threonine-protein kinase Nek3 , EC 2.7.11.1, HSPK 36, Never in mitosis A-related kinase 3, NimA-related protein kinase 3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year
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