NEK5 polyclonal, anti-human
€305.00
In stock
SKU
BS61726
Background:
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. Nek5 (NimA-related protein kinase 5) is a 708 amino acid protein that is related to NIMA, a protein that was originally discovered in Aspergillus nidulans and is necessary for entry into mitosis. One of several members of the Ser/Thr protein kinase super family, Nek5 contains one protein kinase domain through which it catalyzes the ATP-dependent phosphorylation of target proteins. Like NIMA, Nek5 may be involved in mitotic regulation and cell cycle control.
Alternative Name:
Serine/threonine-protein kinase Nek5, Never in mitosis A-related kinase 5, NimA-related protein kinase 5, NEK5
Application Dilution: WB: 1:500~1:1000
Specificity: NEK5 polyclonal antibody detects endogenous levels of NEK5 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 150-200 of Human NEK5.
MW: ~ 81 kDa
Swis Prot.: Q6P3R8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. Nek5 (NimA-related protein kinase 5) is a 708 amino acid protein that is related to NIMA, a protein that was originally discovered in Aspergillus nidulans and is necessary for entry into mitosis. One of several members of the Ser/Thr protein kinase super family, Nek5 contains one protein kinase domain through which it catalyzes the ATP-dependent phosphorylation of target proteins. Like NIMA, Nek5 may be involved in mitotic regulation and cell cycle control.
Alternative Name:
Serine/threonine-protein kinase Nek5, Never in mitosis A-related kinase 5, NimA-related protein kinase 5, NEK5
Application Dilution: WB: 1:500~1:1000
Specificity: NEK5 polyclonal antibody detects endogenous levels of NEK5 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 150-200 of Human NEK5.
MW: ~ 81 kDa
Swis Prot.: Q6P3R8
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review