NELFE Polyclonal Antibody

Background:
The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
NELFE, D6S45, NELF-E, RD, RDBP, RDP

Immunogen: Recombinant fusion protein of human NELFE (NP_002895.3).

Swissprot: P18615
Gene ID: 7936

Calculated MW: 40 kDa/43 kDa
Observed MW: 43 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.