Nephrin (clone 174CT2.1.1), anti-human
€360.00
In stock
SKU
AC-AM1865a
Catalog Number: AC-AM1865a
Size: 0.1 ml
Host: MouseIgM,K
Applications: IF, WB
Datasheet
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Size: 0.1 ml
Host: MouseIgM,K
Applications: IF, WB
Datasheet
Request Information
Background:
This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.
Other Names: Nephrin, Renal glomerulus-specific cell adhesion receptor, NPHS1, NPHN
Target/Specificity:
This Nephrin antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 1088-1117 amino acids from human Nephrin.
Antigen Type: Synthetic Peptide
Antigen Region: 1088-1117
Dilution: 1:10~50
Calculated MW: 134742
NCBI Accession: NP_004637.1
Gene Name: NPHS1
Gene ID: 4868
Primary Accession: O60500
Primary Accession: NP_004637.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.
Other Names: Nephrin, Renal glomerulus-specific cell adhesion receptor, NPHS1, NPHN
Target/Specificity:
This Nephrin antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 1088-1117 amino acids from human Nephrin.
Antigen Type: Synthetic Peptide
Antigen Region: 1088-1117
Dilution: 1:10~50
Calculated MW: 134742
NCBI Accession: NP_004637.1
Gene Name: NPHS1
Gene ID: 4868
Primary Accession: O60500
Primary Accession: NP_004637.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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