Nephrin polyclonal, anti-human, mouse, rat

Background:
Primary steroid resistant nephrotic syndrome (SRNS) is characterized by childhood onset of proteinuria and progression to end stage renal disease. Kidney podocytes and their slit diaphragms form the final barrier to urinary protein loss. Congenital nephrotic syndrome (CNS) is caused by mutations in NPHS1 (nephrin) or NPHS2.

Synonyms: CNF, nephrin, NPHN, NPHS1,

Cellular Location: Cell membrane Single-pass type I membrane protein

Immunogen:
A synthetic peptide of human Nephrin

Gene Symbol: Nephrin

Gene ID: 4868

Swiss prot: O60500

Calculated MW: 100kDa

Recommended dilution:
WB 1:3000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.