Nephrin (Y1193) antibody Blocking Peptide
€363.00
In stock
SKU
AC-BP10417d
Background:
NPHS1 encodes a member of the immunoglobulin family ofcell adhesion molecules that functions in the glomerular filtrationbarrier in the kidney. The gene is primarily expressed in renaltissues, and the protein is a type-1 transmembrane protein found atthe slit diaphragm of glomerular podocytes. The slit diaphragm isthought to function as an ultrafilter to exclude albumin and otherplasma macromolecules in the formation of urine. Mutations in thisgene result in Finnish-type congenital nephrosis 1, characterizedby severe proteinuria and loss of the slit diaphragm and footprocesses.
Other Names:
Nephrin, Renal glomerulus-specific cell adhesion receptor, NPHS1, NPHN
Gene Name: NPHS1
Gene ID: 4868
Primary Accession: O60500
Other Accession: NP_004637.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
NPHS1 encodes a member of the immunoglobulin family ofcell adhesion molecules that functions in the glomerular filtrationbarrier in the kidney. The gene is primarily expressed in renaltissues, and the protein is a type-1 transmembrane protein found atthe slit diaphragm of glomerular podocytes. The slit diaphragm isthought to function as an ultrafilter to exclude albumin and otherplasma macromolecules in the formation of urine. Mutations in thisgene result in Finnish-type congenital nephrosis 1, characterizedby severe proteinuria and loss of the slit diaphragm and footprocesses.
Other Names:
Nephrin, Renal glomerulus-specific cell adhesion receptor, NPHS1, NPHN
Gene Name: NPHS1
Gene ID: 4868
Primary Accession: O60500
Other Accession: NP_004637.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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