Nephrin (Y1210) polyclonal, anti-human, mouse
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In stock
SKU
AC-AP10417a
Catalog Number: AC-AP10417a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB28264
Applications: FC, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB28264
Applications: FC, WB
Datasheet
Request Information
Background:
This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.
Other Names:
Nephrin, Renal glomerulus-specific cell adhesion receptor, NPHS1, NPHN
Target/Specificity:
This Nephrin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1191-1219 amino acids from human Nephrin.
Antigen Region:
1191-1219
Antigen Type: Synthetic Peptide
Gene Name: NPHS1
Gene ID: 4868
Primary Accession: O60500
NCBI Accession: NP_004637.1
Other Accession: NP_004637.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.
Other Names:
Nephrin, Renal glomerulus-specific cell adhesion receptor, NPHS1, NPHN
Target/Specificity:
This Nephrin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1191-1219 amino acids from human Nephrin.
Antigen Region:
1191-1219
Antigen Type: Synthetic Peptide
Gene Name: NPHS1
Gene ID: 4868
Primary Accession: O60500
NCBI Accession: NP_004637.1
Other Accession: NP_004637.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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