Nestin Antibody (S1409) Blocking peptide
€363.00
In stock
SKU
AC-BP2020d
Background:
Nestin is a class VI intermediate filament protein expressed predominantly in stem cells of the neural tube but absent from virtually all differentiated CNS cells. In the CNS, nestin is downregulated upon differentiation and replaced by neurofilaments. Transient expression of nestin has been postulated as a key step committing cells to the neural differentiation pathway. Nestin expression has also been observed in pancreatic hematopoietic stem cell populations.
Other Names:
Nestin, NES
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2020d was selected from the S1409 region of human Phospho-NES. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: NES
Gene ID: 10763
Primary Accession: P48681
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Nestin is a class VI intermediate filament protein expressed predominantly in stem cells of the neural tube but absent from virtually all differentiated CNS cells. In the CNS, nestin is downregulated upon differentiation and replaced by neurofilaments. Transient expression of nestin has been postulated as a key step committing cells to the neural differentiation pathway. Nestin expression has also been observed in pancreatic hematopoietic stem cell populations.
Other Names:
Nestin, NES
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2020d was selected from the S1409 region of human Phospho-NES. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: NES
Gene ID: 10763
Primary Accession: P48681
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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