NET1 Polyclonal Antibody

Background:
This gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms:
NET1, ARHGEF8, NET1A

Immunogen: Recombinant fusion protein of human NET1 (NP_001040625.1).

Swissprot: Q7Z628
Gene ID: 10276

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.