NEU1 Blocking Peptide (Center)

Background:
The protein encoded by this gene is a lysosomal enzymethat cleaves terminal sialic acid residues from substrates such asglycoproteins and glycolipids. In the lysosome, this enzyme is partof a heterotrimeric complex together with beta-galactosidase andcathepsin A (the latter is also referred to as 'protectiveprotein'). Mutations in this gene can lead to sialidosis, alysosomal storage disease that can be type 1 (cherry redspot-myoclonus syndrome or normosomatic type), which is late-onset,or type 2 (the dysmorphic type), which occurs at an earlier agewith increased severity.

Other Names:
Sialidase-1, Acetylneuraminyl hydrolase, G9 sialidase, Lysosomal sialidase, N-acetyl-alpha-neuraminidase 1, NEU1, NANH

Target/Specificity:
The synthetic peptide sequence is selected from aa 203-214 of HUMAN NEU1

Gene Name: NEU1

Gene ID: 4758
Primary Accession: Q99519
Other Accession: A6BMK7; NP_000425.1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.