Neuregulin-3 Polyclonal Antibody
€0.00
In stock
SKU
ELK-ES8415
Catalog Number: ELK-ES8415
Reactivity: Human, Mouse
Applications: WB, IHC-p, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Reactivity: Human, Mouse
Applications: WB, IHC-p, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Background:
neuregulin 3(NRG3) Homo sapiens This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis. Linkage studies have implicated this gene as a susceptibility locus for schizophrenia and schizoaffective disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcri
Alternative Names:
NRG3, Pro-neuregulin-3, membrane-bound isoform, Pro-NRG3
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human NRG3. AA range:311-360
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 80
GeneID: NRG3
Storage: -20°C/1 year
NOTE: For Research Use Only
neuregulin 3(NRG3) Homo sapiens This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis. Linkage studies have implicated this gene as a susceptibility locus for schizophrenia and schizoaffective disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcri
Alternative Names:
NRG3, Pro-neuregulin-3, membrane-bound isoform, Pro-NRG3
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human NRG3. AA range:311-360
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 80
GeneID: NRG3
Storage: -20°C/1 year
NOTE: For Research Use Only
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