Neurexophilin-2 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60193
Background:
Neurexophilin-1 (also known as NPH1 or NXPH1), Neurexophilin-2 (also known as NPH2 or NXPH2) and Neurexophilin-3 (also known as NPH3 or NXPH3) are members of the Neurexophilin family (Neurexophilin-1-4) of neuropeptide-like glycoproteins that are proteolytically processed after synthesis. Neurexophilin-1-3 are secreted proteins that are thought to function as signaling molecules which specifically bind to target proteins, such as neurexin Iα (a protein that promotes adhesion between dendrites and axons), and are essential for proper neurotransmitter release. While Neurexophilin-1 is located primarily in spleen tissue, Neurexophilin-2 is expressed primarily in kidney and both Neurexophilin-2 and Neurexophilin-3 are highly expressed in brain. Defects in the gene encoding Neurexophilin-1 may be associated with schizophrenia, a mental disorder characterized by an abnormal perception of reality.
Alternative Name:
Neurexophilin 2, Neurexophilin2, NXPH2, NPH2
Application Dilution: WB: 1:500~1:1000
Specificity: Neurexophilin-2 polyclonal antibody detects endogenous levels of Neurexophilin-2 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human Neurexophilin-2.
MW: ~ 30 kDa
Swis Prot.: O95156
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Neurexophilin-1 (also known as NPH1 or NXPH1), Neurexophilin-2 (also known as NPH2 or NXPH2) and Neurexophilin-3 (also known as NPH3 or NXPH3) are members of the Neurexophilin family (Neurexophilin-1-4) of neuropeptide-like glycoproteins that are proteolytically processed after synthesis. Neurexophilin-1-3 are secreted proteins that are thought to function as signaling molecules which specifically bind to target proteins, such as neurexin Iα (a protein that promotes adhesion between dendrites and axons), and are essential for proper neurotransmitter release. While Neurexophilin-1 is located primarily in spleen tissue, Neurexophilin-2 is expressed primarily in kidney and both Neurexophilin-2 and Neurexophilin-3 are highly expressed in brain. Defects in the gene encoding Neurexophilin-1 may be associated with schizophrenia, a mental disorder characterized by an abnormal perception of reality.
Alternative Name:
Neurexophilin 2, Neurexophilin2, NXPH2, NPH2
Application Dilution: WB: 1:500~1:1000
Specificity: Neurexophilin-2 polyclonal antibody detects endogenous levels of Neurexophilin-2 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human Neurexophilin-2.
MW: ~ 30 kDa
Swis Prot.: O95156
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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