Neurofascin polyclonal, anti-human, mouse, rat, hamster, dog, bovine, rabbit, chimpanzee, monkey, horse

Protein Family: CAM Ligands, Cell Adhesion Molecules

Pathway and Disease: Nervous and Sensory Systems, Signaling Molecules and Interaction

Description:
Neurofascin is a cell adhesion ankyrin-binding protein, which is involved in neurite extension, axonal guidance, synaptogenesis, myelination and neuron-glial cell interactions. Neurofascin is strongly but transiently up-regulated in oligodendrocytes at the onset of myelinogenesis. The expression declines abruptly once the oligodendrocytes have engaged their target exons. Shorter isoforms (NF155) are also observed. This antibody binds to precursor and NF155 forms.

Alternate Names: Neurofascin, NFASC, Neurofascin-155, NF186, NF155

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: O94856

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human neurofascin.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.