Neurogenin-2 polyclonal, anti-human, mouse, rat

Protein Family: Transcription Factors

Pathway and Disease: Neurodegenerative Disorders, Development and Behavior, Transcription

Description:
Neurogenins are a family of bHLH transcription factors involved in specifying neuronal differentiation. They are related to Drosophila atonal. Neurogenin-2 is essential for the development of the dentate gyrus, a region of the hippocampus which is involved in learning and memory. Neurogenin-2 mutant mice have fewer DG progenitors and these cells present defects in neuronal differentiation.

Alternate Names: Neurogenin-2, NGN-2, Protein atonal homolog 4, Class A basic helix-loop-helix protein 8, bHLHa8, NEUROG2, ATOH4, BHLHA8, NGN2

Application Notes: E: 1:10,000-1:50,000; WB: 1:200-1:1,000; IHC: 1:50-1:200

Accession No.: Q9H2A3

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human neurogenin-2.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.5% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.