Neurogenin2 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP2023a
Background:
Neurogenin-2 is a member of the neurogenin subfamily of basic helix-loop-helix (bHLH) transcription factor genes that play an important role in neurogenesis from migratory neural crest cells. In the course of mouse neurogenesis, Ngn2 and Ngn1 are expressed in distinct progenitor populations residing in the central and peripheral nervous systems. Mutation analyses demonstrate that Ngn1 is required for the determination of neuronal precursors for proximal cranial sensory ganglia and that Ngn2 is necessary for the determination of precursors for epibranchial placode-derived sensory neurons.
Other Names:
Neurogenin-2, NGN-2, Class A basic helix-loop-helix protein 8, bHLHa8, Protein atonal homolog 4, NEUROG2, ATOH4, BHLHA8, NGN2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2023a was selected from the N-term region of human Neurogenin2 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: NEUROG2
Gene ID: 63973
Primary Accession: Q9H2A3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Neurogenin-2 is a member of the neurogenin subfamily of basic helix-loop-helix (bHLH) transcription factor genes that play an important role in neurogenesis from migratory neural crest cells. In the course of mouse neurogenesis, Ngn2 and Ngn1 are expressed in distinct progenitor populations residing in the central and peripheral nervous systems. Mutation analyses demonstrate that Ngn1 is required for the determination of neuronal precursors for proximal cranial sensory ganglia and that Ngn2 is necessary for the determination of precursors for epibranchial placode-derived sensory neurons.
Other Names:
Neurogenin-2, NGN-2, Class A basic helix-loop-helix protein 8, bHLHa8, Protein atonal homolog 4, NEUROG2, ATOH4, BHLHA8, NGN2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2023a was selected from the N-term region of human Neurogenin2 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: NEUROG2
Gene ID: 63973
Primary Accession: Q9H2A3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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