Neuropeptide FF

Protein Family: Hormones

Pathway and Disease: Development and Behavior, Nervous and Sensory Systems, Signaling Molecules and Interaction

Alternate Names: Pro-FMRFamide-related neuropeptide FF; NPFF; Neuropeptide FF; Rfamide peptide; FMRFamide-related peptides

Accession No.: O15130

Description:
Neuropeptide FF (NPFF) is an endogenous RFamide peptide that was initially identified to attenuate morphine-induced analgesia. NPFF has been shown to have wider effects, including elevation of arterial blood pressure and somatostatin secretion from the pancreas as well as anorexigenic effects. NPFF potentiates and sensitizes ASIC1 and ASIC3 channels. NPFF binds to NPFF1 and NPFF2 receptors.

Format:
Each vial contains 5 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.

MW: 1081.3 g/mol

Sequence:
Human: H-Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2 or H-FLFQPQRF-NH2

Composition:
C54H76N14O10

Purity:
> 95% by HPLC

Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.