Neurotrophin-3 polyclonal, anti-human, mouse, rat

Protein Family: Cytokines

Pathway and Disease: Signal Transduction, Nervous and Sensory Systems

Description:
Neurotrophin-3 is a neurotrophic factor in the NGF (Nerve Growth Factor) family of neurotrophins. Neurotrophin-3 is a protein growth factor which has activity on certain neurons of the peripheral and central nervous system: it helps to support the survival and differentiation of existing neurons, and encourages the growth and differentiation of new neurons and synapses. Mice born without the ability to make NT-3 have loss of proprioceptive and subsets of mechanoreceptive sensory neurons.

Alternate Names: Neurotrophin-3, NT-3, Neurotrophic factor, HDNF, Nerve growth factor 2, NGF-2, NTF3

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P20783

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human neurotrophin-3.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 50% glycerol with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.