Neurotrophin-4/5 polyclonal, anti-human, mouse, rat

Protein Family: Cytokines

Pathway and Disease: Nervous and Sensory Systems, Signal Transduction

Description:
Neurotrophin-4/5 (NT-4/5) is a neurotrophic factor that signals predominantly through the TrkB receptor tyrosine kinase. Neurotrophins function primarily to regulate naturally occurring cell death of neurons during development. Two additional structurally homologous neurotrophic factors have been identified: brain-derived neurotrophic factor (BDNF) and neurotrophic 3 (NT-3).

Alternate Names: Neurotrophin-4, NT-4, Neurotrophic factor 4, Neurotrophin-5, NT-5, NTF4, NTF5

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Accession No.: P34130

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human NT-4/5.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.