NF-E4 (Acetyl Lys43) Polyclonal Antibody

Background:
nuclear factor, erythroid 4(NFE4) Homo sapiens The erythroid-specific protein encoded by this gene, and the ubiquitous transcription factor CP2, form the stage selector protein (SSP) complex, which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells. Alternate use of an in-frame upstream non-AUG (CUG) translation initiation codon, and a downstream AUG codon, results in two isoforms. While the long isoform (22 kDa) acts as an activator, the short isoform (14 kDa) has been shown to repress gamma-globin gene expression. This gene is located in an intron of the FBXL13 gene on the opposite strand. [provided by RefSeq, Jul 2008],

Alternative Names:
NFE4, Transcription factor NF-E4

Immunogen: Synthesized acetyl-peptide derived from the human NF-E4 around the acetylation site of K43.

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 19

GeneID: NFE4

Storage: -20°C/1 year

NOTE: For Research Use Only