NF-H (clone ), anti-human, mouse, rat, pig

Protein Family: Cytoskeleton Proteins

Pathway and Disease: Neurodegenerative Disorders

Description:
Neurofilament heavy polypeptide (NF-H) has an important role in the function of mature axons that is not subserved by the two smaller NF proteins. Defects in NF-H are a cause of susceptibility to amyotrophic lateral sclerosis (ALS). ALS is a neurodegenerative disorder affecting upper and lower motor neurons, resulting in fatal paralysis.

Alternate Names: NF-H, NF200, Neurofilament heavy polypeptide, Neurofilament triplet H protein, 200 kDa neurofilament protein, NEFH, KIAA0845, NFH

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P12036

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the enzymatically dephosphorylated C-term region of pig NF-H.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.