NF1 Peptide

NF1 Peptide

€100.00
In stock
SKU
350512
Catalog Number: 350512
Size: 0.1 mg
Datasheet
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Protein Family: Enzymes

Pathway and Disease: Cancers, Signal Transduction

Alternate Names: Neurofibromin; Neurofibromatosis-related protein NF-1; Neurofibromin truncated; NF1

Accession No.: P21359, NP_001035957

Description:
Neurofibromin (NF1) stimulates the GTPase activity of Ras. Defects in NF1 are the cause of different types neurofibromatosis, colorectal cancer, and juvenile myelomonocytic leukemia.

Format:
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.

MW: 1929.1 g/mol

Sequence:
The synthetic peptide used to raise the antibody Cat. No. 200150 is selected from a sequence within the center region of human NF1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.

Composition:
C79H133N25O29S1

Purity:
> 80% by HPLC

Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
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