NF1 polyclonal, anti-human, mouse, rat

Background:
This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.

Synonyms: WSS, NFNS, VRNF

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human NF1

Gene Symbol: NF1

Gene ID: 4763

Swiss prot: P21359

Calculated MW: 319 kDa

Recommended dilution:
WB 1:200-1000, IHC 1:25-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.